longkanker -lung cancerlongkanker -lung cancer
longkanker -lung cancer
longkanker -lung cancer longkanker -lung cancer
  
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longkanker -lung cancer

Clinical trials

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Ongoing Protocols: (update 06/12/2011)
 
NON-SMALL CELL LUNG CANCER
.
staging
 
Aster 2
The value of baseline echo-endoscopic mediastinal staging in clinical N1 lung cancer.
 
PET-CT restaging validationstudy
PET-CT imaging for early response prediction and prognostic value of combined morphometric-pathologic response in mediastinal lymphnodes and primary tumor response on serial PET-CT in patients receiving induction chemotherapy for operable stage IIIA-N2 non-small cell lung cancer
 
non-advanced
  
MAGRIT (GSK)
A double blind, randomized, placebo-controlled phase III study to assess the efficacy of recMAGE-A3+ AS15 antigen-specific cancer immunotherapeutic as adjuvant therapy in patients with resectable MAGE-A3-positive NSCLC.
  
PROCLAIM (Lilly)
A phase 3 Study of Pemetrexed, Cisplatin, and Radiotherapy Followed by Consolidation Pemetrexed versus Etoposide, Cisplatin, and Radiotherapy Followed by Consolidation Cytotoxic Chemotherapy of Choice in Patients with Unresectable, locally Advanced, Stage III NSCLC Other than Predominantly squamous Cell Histology.
  
advanced first line
 
CERTO (Merck)
Open-label, randomized, controlled, multicenter Phase II study investigating 2 cilengitide regimens in combination with cetuximab and platinum-based chemotherapy (cisplatin/vinorelbine or cisplatin/gemcitabine) compared to cetuximab and platinum-based chemotherapy alone as first-line treatment for patients with advanced NSCLC.
.
RO5083945 (Roche)
A randomized, multicenter, open-label phase IB/II study of RO5083945 in combination with cisplatin and gemcitabine/pemetrexed in patients with advanced or recurrent NSCLC who have not received prior chemotherapy.
.    
second or third line
.
LDK378 (Novartis)
A phase I, multicenter, open-label dose escalation study of LDK378, administered orally in adult patients with tumors characterized by genetic abnormalities in anaplastic lymphoma kinase(ALK).
 
BKM120 (Novartis)
An open label two-stage study of orally adminstered BKM120 in patients with metastatic NSCLC with activated PI3K pathway
SMALL CELL LUNG CANCER  
 
MESOTHELIOMA
 
SAKK
Neo-adjuvant chemotherapy and extrapleural pneumonectomy of malignant pleural mesothelioma with or without hemithoracic radiotherapy. A randomized multicenter phase II trial.
 
OTHERS
 
NELSON
Nederlands-Leuvens Longkanker Screening Onderzoek.
A Randomised Clinical Trial for Lung Cancer Screening in High Risk Subjects 2003-2006

For further information regarding protocols or clinical trial unit description, please contact the datamanagers:

 

beatrijs.anrijs@uzleuven.be

 
christel.oyen@uzleuven.be

 
liesbet.peeters@uzleuven.be

 
 

 
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